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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPA1
All Species:
22.12
Human Site:
Y82
Identified Species:
48.67
UniProt:
O60313
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60313
NP_056375.2
960
111631
Y82
F
S
P
I
K
Y
G
Y
Q
P
R
R
N
F
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087037
1092
125633
Y159
F
S
P
I
K
Y
G
Y
Q
P
R
R
N
F
W
Dog
Lupus familis
XP_534321
1175
133763
Y242
L
S
P
I
K
Y
G
Y
Q
P
R
R
N
F
W
Cat
Felis silvestris
Mouse
Mus musculus
P58281
960
111321
Y82
L
S
P
I
K
Y
G
Y
Q
P
R
R
N
F
W
Rat
Rattus norvegicus
Q2TA68
960
111289
Y82
L
S
P
T
K
Y
G
Y
Q
P
R
R
N
F
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F499
977
113427
Y81
L
L
N
V
K
Y
G
Y
Q
S
Y
R
N
F
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3A7
966
111315
Y81
S
R
S
G
G
H
G
Y
Q
Q
H
R
T
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610941
933
107185
P74
R
G
W
Q
M
P
P
P
S
R
G
Y
G
M
L
Honey Bee
Apis mellifera
XP_396882
918
106720
I74
I
L
K
G
A
L
K
I
R
Y
L
L
L
G
G
Nematode Worm
Caenorhab. elegans
NP_495986
964
110236
I88
L
L
K
L
R
Y
F
I
A
T
G
V
I
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32266
881
99159
G80
L
P
I
Y
V
G
G
G
M
A
A
A
G
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.4
79.5
N.A.
96.3
95.9
N.A.
N.A.
85.6
N.A.
79
N.A.
52.1
55
50.9
N.A.
Protein Similarity:
100
N.A.
87.6
80.5
N.A.
97.9
97.8
N.A.
N.A.
92.3
N.A.
88.8
N.A.
69
73.9
69.2
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
60
N.A.
40
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
66.6
N.A.
46.6
N.A.
0
6.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
10
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
19
0
0
0
0
0
10
0
0
0
0
0
0
64
0
% F
% Gly:
0
10
0
19
10
10
73
10
0
0
19
0
19
19
19
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
10
37
0
0
0
19
0
0
0
0
10
0
0
% I
% Lys:
0
0
19
0
55
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
55
28
0
10
0
10
0
0
0
0
10
10
10
0
10
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
55
0
0
% N
% Pro:
0
10
46
0
0
10
10
10
0
46
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
64
10
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
0
0
0
10
10
46
64
0
0
0
% R
% Ser:
10
46
10
0
0
0
0
0
10
10
0
0
0
10
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
64
% W
% Tyr:
0
0
0
10
0
64
0
64
0
10
10
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _